EE 519 - MEDICAL IMAGING

                     2012-2013 Academic Year -  Spring Semester

Instructor: Murat Eyüboglu
Office: DZ-09
Credit Hours: (3-0) 3
 

Catalogue Description:  Image reconstruction with non-diffracting sources in two dimensions, image reconstruction with non-diffracting sources in three dimensions, algebraic reconstruction algorithms.  Magnetic Resonance Imaging (MRI) techniques, flow imaging and flow related MRI.Ultrasonic computed tomography, tomographic imaging with diffracting sources, ultrasonic reflection tomography.  Nuclear tomographic imaging.  New imaging modalities.

Recommended Prerequisites: EE 415 Introduction to Medical Imaging.

IMPORTANT NOTE:

To be able to eligible for the final exam, students should take all the midterm exams, turn in the term project on due date. In addition to that requirement,

  1. the minimum score of 40 over 100 should be obtained from the midterm exams,
  2. the minimum score of 40 over 100  should be obtained from the term project.

 

Students who do not take any one of the midterm exam or the final exam or do not turn in their term projects on due date will be graded with “NA”.

Students who are graded with “NA” will not be eligible for the RESIT EXAM.

Grading policy

Midterm  Exam

30% 

Term Projects 

30%

Homeworks / Class Perf.

  5%

Final Exam 

35%

 

Textbooks:

Authors

Title

Publisher

Year

M. Eyuboglu

Lecture Notes

 

2001

Avinash C. Kak, Malcolm Slaney
Available in pdf format at:
http://www.slaney.org/pct/index.html

Principles of Computerized 
Tomographic Imaging

IEEE Press, New York

1988

Z.H. Cho, J.P. Jones and M. Singh

Foundations of Medical Imaging

Wiley, NewYork

1993

Zhi-Pei Liang and Paul Lauterbur

Principles of Magnetic Resonance Imaging 
(MRI):A signal processing perspective

IEEE Press, New York

1999

Reference Books:

Authors

Title

Publisher

Year

Albert Macowski

Medical Imaging Systems

Prentice-Hall, New Jersey

1983

Gabor T. Herman

Image Reconstruction from Projections; The Fundamentals of
Computerized Tomography

Academic Press, NewYork

1980

K. Kirk Shung, Michael B. Smith, Benjamin Tsui

Principles of Medical Imaging

Academic Press, Inc., London

1992

V. Kuperman

Magnetic Resonance Imaging-Physical Principles 
and Applications

Academic Press, NewYork

2000

Tentative Course Syllabus

 

WEEK

Introduction – Signal and image processing fundamentals. (Textbook 1: Sec. 2.1, 2.2, 5.1) 

Reading assignment..

1

Image reconstruction with non-diffracting sources in two dimensions: Radon transform, central section theorem, inverse radon transform, filtered backprojection, reconstruction from fan beam projections, reconstruction from a limited number of views. (Textbook 1: Sec. 3.1, 3.2, 3.3, 3.4, 3.5)

2-3

Image reconstruction with non-diffracting sources in three dimensions: True three dimensional reconstruction algorithm for the complete sphere, true three dimensional reconstruction algorithm of generalized form, planar-integral projection reconstruction. (Textbook 1: Sec. 3.6) 

3

Algebraic reconstruction algorithms: Algebraic reconstruction techniques, simultaneous iterative reconstruction technique, simultaneous algebraic reconstruction technique. (Textbook 1: Sec. 7.1, 7.2, 7.3, 7.4) 

4


5. Fundamentals of Nuclear Magnetic Resonance:  Physical fundamentals of NMR, Mathematics of magnetic resonance, Bloch equation, gradient fileds, rf field, rotating frame, spin relaxation (textbook 2 and 3) (3 lectures)

5

6. MRI techniques: Conventional imaging sequences, saturation, partial saturation, inversion recovery, spin echo techniques, T1 and T2 weighted imaging, practical pulse sequence design (textbook 2 and 3) 
(4 lectures)

6-7

 7. MRI Hardware: (lecture notes) (1 lecture)

7

8. MR Multi slice imaging:  Projection data measurement in MRI, multislice imaging (textbook 2 and 3) (2 lectures)

8

9. MR High speed imaging:  Echo-planar imaging (EPI), spiral scan EPI, square spiral scan EPI, Gradient echo imaging, SSFP imaging (textbook 2 and 3) (2 lectures)

8-9

10. Data space, k-space and image space in MRI: : (lecture notes) (1 lecture)

9

11. Flow imaging and flow related MRI: Principles of bulk flow imaging, flow compensation in imaging, microscopic flow imaging, angiography. (textbook 2 and 3) (1 lecture)

10

12. MR microscopy and high-resolution imaging. (textbook 2 and 3) (1 lecture)

10

13. Tomographic imaging with diffracting sources: Diffracted projections, approximations to the wave equations, the Fourier diffraction theorem, interpolation and filtered backprojection algorithm for diffracting sources, limitations, evaluations of reconstruction algorithms, experimental limitations. (textbook 1) (6 lectures)

11-12

14. Ultrasonic reflection tomography: B-scan imaging, reflection tomography, reflection vs. diffraction tomography, reflection tomography with point transmitter/receiver. (textbook 1)

13

15. Ultrasonic computed tomography: Ultrasonic refractive index tomography, ultrasonic attenuation tomography. (textbook 1) (6 lectures)

13-14

6.  Emerging medical imaging modalities. (1 lecture)

14